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has been cited by the following article:

• TITLE: Local Adjuvants in Surgical Management of Bone Lesions

  AUTHORS: Giulio Di Giacomo, Antonio Ziranu, Carlo Perisano, Andrea Piccioli, Giulio Maccauro

  KEYWORDS: Local Adjuvant, Bone Lesions, Orthopaedic Oncology, Cryotherapy

  JOURNAL NAME: Journal of Cancer Therapy, Vol.6 No.6, May 29, 2015

  ABSTRACT: One of the most common methods for surgical treatment of bone metastasis is curettage. Local adjuvants are used to improve the effect of curettage in local cancer surgery and they may exerted their effects either chemically either physically; in orthopaedic oncology the most common are phenol, liquid nitrogen, laser, cement and argon beam coagulation. The purpose of this article is to review the main characteristics of the most common chemical and physical agents used in bone oncology, emphasizing the toxic effects of some of them, especially phenol and liquid nitrogen.