Chen, W.D., Liang, Y., Li, H., Xiong, Y., Liu, X., Wang, G.J. and Xie, L. (2006) Simple, Sensitive and Rapid LC-ESI-MS Method for the Quantitation of Iloperidone in Human Plasma-Application to Pharmacokinetic Studies. Journal of Pharmaceutical and Biomedical Analysis, 41, 256-260.
http://dx.doi.org/10.1016/j.jpba.2005.10.008

has been cited by the following article:

• TITLE: Development and Validation of RP-UPLC Method for the Determination of Iloperidone, Its Related Compounds and Degradation Products in Bulk and Dosage Form

  AUTHORS: Shashikant B. Landge, Sanjay A. Jadhav, Shrihari P. Vishwambar, Pavankumar V. Solanki, Saroj R. Bembalkar, Vijayavitthal T. Mathad

  KEYWORDS: Iloperidone, UPLC, Degradation, RSD and Validation, Stability Indicating

  JOURNAL NAME: American Journal of Analytical Chemistry, Vol.5 No.14, October 29, 2014

  ABSTRACT: A rapid, specific, sensitive, and precise reverse-phase UPLC method developed for the quantitative determination of an atypical antipsychotic drug Iloperidone and its eight potential impurities in drug substances and drug products is described in this report. Chromatographic separation was achieved on a Waters Acquity UPLC® HSS C18 (2.1 mm × 100 mm, 1.8 micron) column thermostated at 35°C with a short runtime of 10 min. Quantification is achieved with photodiode array detection at 225 nm over the concentration range of 0.03 - 0.15 μg/mL. Forced degradation study was carried out under acidic, alkaline, oxidative, photolytic and thermal conditions to demonstrate the stability-indicating capability of the developed UPLC method. Comparison of system performance with conventional high-performance liquid chromatography is made with respect to analysis time, efficiency, and sensitivity. The method is validated according to the ICH guidelines and is applied successfully for the determination of Iloperidone in tablets.