TITLE:
Anti-oxidant activity and cytotoxicity of ethanolic extracts from rhizome of Musa acuminata
AUTHORS:
KPS Adinarayana, P Ajay Babu
KEYWORDS:
Antioxidant; Antiproliferative; DPPH; Free Radical; MTT Assay
JOURNAL NAME:
Natural Science,
Vol.3 No.4,
April
20,
2011
ABSTRACT: In the present study, antioxidant activities of rhizome of Musa acuminata were investigated. Free radical scavenging assay (DPPH) and reducing power of the ethanolic extract of banana rhizome resulted in potential antioxidant activities. A relatively high percentage of antioxidant activity by DPPH assay (81.41% at 200 μg/ml) which was comparable to that of the standard, ascorbic acid at 100 μg/ml was observed. With the gallic acid as standard the extract showed a relatively low reductive potential, however, when tested for cytotoxicity at the highest concentration of the tested dose (256 μg/ml), the maximum rate of inhibition observed was 50.32%. The present work indicates that the ethanolic extract of Musa acuminata exhibits significant antiproliferative and antioxidant activities.