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has been cited by the following article:

• TITLE: Fluorine-18 Radiochemistry: A Novel Thiol-Reactive Prosthetic Group, [18F]FBAMPy

  AUTHORS: Thomas M. Moore, Murthy R. Akula, George W. Kabalka

  KEYWORDS: Radiochemistry, Prosthetic Group, PET, Fluorine-18

  JOURNAL NAME: Natural Science, Vol.8 No.1, January 27, 2016

  ABSTRACT: A novel thiol-reactive bifunctional agent, an analogue of fluorobenzaldehyde-O-[6-(2,5-dioxo-2,5- dihydro-pyrrol-1-yl)-hexyl]oxime, (FBAM) has been synthesized. The new prosthetic group, [18F]- FBAMPy, replaces the 4-fluorophenyl moiety with a 2-fluoropyridinyl moiety leading to increased polarity (FBAM analytical HPLC Rf = 6.4 min; FBAMPy Rf = 4.8 min) while retaining the sulfur-reactive pendant. By altering the polarity of the molecule, this new prosthetic group should have significant impact in coupling it with small peptides and other biomolecules.