Dr. Mohan Maddur Sathyanarayana

Vaccine Research and Development, Pfizer Inc., USA

Email: mohanms.manu@gmail.com, mmaddur@emory.edu

Qualifications

2008-2011 Ph.D. Pierre and Marie Curie University, France

2004-2006 M.V.Sc. Indian Veterinary Research Institute, India

1998-2003 D.V.M University of Agricultural Sciences, India

Publications (Selected)

1. Modjarrad K, Che Y, Chen W, Maddur M S, et al. Preclinical characterization of the Omicron XBB. 1.5-adapted BNT162b2 COVID-19 vaccine. npj Vaccines, 2024, 9(1): 229.
2. Hauguel T, Sharma A, Mastrocola E, Maddur M S, et al. Preclinical immunogenicity and safety of hemagglutinin-encoding modRNA influenza vaccines. npj Vaccines, 2024, 9(1): 183.
3. Baber J, Arya M, Moodley Y, Maddur M S, et al. A phase 1/2 study of a respiratory syncytial virus prefusion F vaccine with and without adjuvant in healthy older adults. The Journal of Infectious Diseases, 2022, 226(12): 2054-2063.
4. Schmoele-Thoma B, Zareba A M, Jiang Q, Maddur M S, et al. Vaccine efficacy in adults in a respiratory syncytial virus challenge study. New England Journal of Medicine, 2022, 386(25): 2377-2386.
5. Vogel A B, Kanevsky I, Che Y, Maddur M S, et al. BNT162b vaccines protect rhesus macaques from SARS-CoV-2. Nature, 2021, 592(7853): 283-289.
6. Vogel A B, Kanevsky I, Che Y, Maddur M S, et al. BNT162b vaccines are immunogenic and protect non-human primates against SARS-CoV-2. bioRxiv, 2020: 2020.12. 11.421008.
7. Vogel A B, Kanevsky I, Che Y, Maddur M S, et al. A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates. BioRxiv, 2020: 2020.09. 08.280818.
8. Maddur M S, Lacroix-Desmazes S, Dimitrov J D, et al. Natural antibodies: from first-line defense against pathogens to perpetual immune homeostasis. Clinical Reviews in Allergy & Immunology, 2020, 58: 213-228.
9. Hagan T, Cortese M, Rouphael N, Maddur M S, et al. Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans. Cell, 2019, 178(6): 1313-1328. e13.
10. Galeotti C, Stephen-Victor E, Karnam A, Maddur M S, et al. Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE. Journal of Allergy and Clinical Immunology, 2019, 144(2): 524-535. e8.
11. Maddur M S, Kaveri S V, Bayry J. Induction of human dendritic cell maturation by naïve and memory B-cell subsets requires different activation stimuli. Cellular & Molecular Immunology, 2018, 15(12): 1074-1076.
12. Sharma M, Das M, Stephen-Victor E, Maddur M S, et al. Regulatory T cells induce activation rather than suppression of human basophils. Science immunology, 2018, 3(23): eaan0829.
13. Maddur M S, Stephen-Victor E, Das M, et al. Regulatory T cell frequency, but not plasma IL-33 levels, represents potential immunological biomarker to predict clinical response to intravenous immunoglobulin therapy. Journal of Neuroinflammation, 2017, 14: 1-8.
14. Maddur M S, Kaveri S V, Bayry J. Circulating normal IgG as stimulator of regulatory T cells: lessons from intravenous immunoglobulin. Trends in immunology, 2017, 38(11): 789-792.
15. Maddur M S, Bayry J. B cells drive Th2 responses by instructing human dendritic cell maturation. Oncoimmunology, 2015, 4(5): e1005508.
16. Maddur M S, Trinath J, Rabin M, et al. Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation. Cellular & molecular immunology, 2015, 12(5): 650-652.

Profile Details

https://orcid.org/0000-0002-7085-1762

https://scholar.google.com/citations?user=GYWJhpQAAAAJ&hl=en

https://www.researchgate.net/profile/Mohan-Maddur

https://www.linkedin.com/in/mohan-maddur-0493a011/

WoS ResearcherID: E-4763-2015