[1]
|
Weiss, R.A. (1993) How Does HIV Cause AIDS? Science, 260, 1273-1279. http://dx.doi.org/10.1126/science.8493571
|
[2]
|
Douek, D.C., Roederer, M. and Koup, R.A. (2009) Emerging Concepts in the Immunopathogenesis of AIDS. Annual Review of Medicine, 60, 471-484. http://dx.doi.org/10.1146/annurev.med.60.041807.123549
|
[3]
|
UNAIDS, WHO (2007) 2007 AIDS Epidemic Update (PDF). 10.
|
[4]
|
Cunningham, A.L., Donaghy, H., Harman, A.N., Kim, M. and Turville, S.G. (2010) Manipulation of Dentric Cell Function by Viruses. Currentopinion in Microbiology, 13, 524-529. http://dx.doi.org/10.1016/j.mib.2010.06.002
|
[5]
|
Doitsh, G., Galloway, N.L.K., Geng, X., Yang, Z.Y., Monrole, K.M., Zepeda, O., Hunt, P.W., Hatano, H., Sowinski, S., Isa, M.-A. and Green, W.C. (2014) Cell Death by Pyroptosis Drives CD4 T-Cell Depletion in HIV-1 Infection. Nature, 505, 509-514.
|
[6]
|
Kumar, V. (2012) Robbins Basic Pathology. 9th Edition, 147.
|
[7]
|
Cohen, M.S., Hellmann, N., Levy, J.A., De Cock, K. and Lange, J. (2008) The Spread, Treatment, and Prevention of HIV-1: Evolution of a Global Pandemic. The Journal of Clinical Investigation, 118, 1244-1254. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276790/
|
[8]
|
“Fact Sheet” UNAIDS.org. 2013.
|
[9]
|
UNAIDS (2011) 1-10.
|
[10]
|
UNAIDS (2014) The Gap Report 2014.
|
[11]
|
Kuller, L.H., Tracy, R., Belloso, W., De Wit, S., Drummond, F., Lane, H.C., Ledergerber, B., Lundgren, J., Neuhaus, J., Nixon, D., et al., INSIGHT SMART Study Group (2008) Inflammatory and Coagulation Biomarkers and Mortalityin Patients with HIV Infection. PLoS Medicine, 5, e203. http://dx.doi.org/10.1371/journal.pmed.0050203
|
[12]
|
Duprez, D.A., Neuhaus, J., Kuller, L.H., Tracy, R., Belloso, W., De Wit, S., Drummond, F., Lane, H.C., Ledergerber, B., Lundgren, J., et al., INSIGHTSMART Study Group (2012) Inflammation, Coagulation and Cardiovascular Disease in HIV-Infected Individuals. PLoS ONE, 7, e44454. http://dx.doi.org/10.1371/journal.pone.0044454
|
[13]
|
Cushman, M., Lemaitre, R.N., Kuller, L.H., Psaty, B.M., Macy, E.M., Sharrett, A.R. and Tracy, R.P. (1999) Fibrinolytic Activation Markers Predict Myocardial Infarction in the Elderly. The Cardiovascular Health Study. Arteriosclerosis, Thrombosis, and Vascular Biology, 19, 493-498. http://dx.doi.org/10.1161/01.ATV.19.3.493
|
[14]
|
Cushman, M., Folsom, A.R., Wang, L., Aleksic, N., Rosamond, W.D., Tracy, R.P. and Heckbert, S.R. (2003) Fibrin Fragment D-Dimer and the Risk of Future Venous Thrombosis. Blood, 101, 1243-1248. http://dx.doi.org/10.1182/blood-2002-05-1416
|
[15]
|
Ford, E.S., Greenwald, J.H., Richterman, A.G., Rupert, A., Dutcher, L., Badralmaa, Y., Natarajan, V., Rehm, C., Hadigan, C. and Sereti, I. (2010) Traditionalrisk Factors and D-Dimer Predict Incident Cardiovascular Disease Events Inchronic HIV Infection. AIDS, 24, 1509-1517. http://dx.doi.org/10.1097/QAD.0b013e32833ad914
|
[16]
|
Jong, E., Louw, S., Meijers, J.C., de Kruif, M.D., ten Cate, H., Buller, H.R., Mulder, J.W. and van Gorp, E.C. (2009) The Hemostatic Balance in HIV-Infected Patients with and without Antiretroviral Therapy: Partial Restoration with Antiretroviral Therapy. AIDS Patient Care and STDS, 23, 1001-1007. http://dx.doi.org/10.1089/apc.2009.0173
|
[17]
|
Ledwaba, L., Tavel, J.A., Khabo, P., Maja, P., Qin, J., Sangweni, P., Liu, X., Follmann, D., Metcalf, J.A., Orsega, S., et al. and Project Phidisa Biomarkers Team (2012) Pre-ART Levels of Inflammation and Coagulation Markers Are Strong Predictors of Death in a South African Cohort with Advanced HIV Disease. PLoS ONE, 7, e24243. http://dx.doi.org/10.1371/journal.pone.0024243
|
[18]
|
Musselwhite, L.W., Sheikh, V., Norton, T.D., Rupert, A., Porter, B.O., Penzak, S.R., Skinner, J., Mican, J.M., Hadigan, C. and Sereti, I. (2011) Markers of Endothelial Dysfunction, Coagulation and Tissue Fibrosis Independently Predictvenous Thromboembolism in HIV. AIDS, 25, 787-795. http://dx.doi.org/10.1097/QAD.0b013e3283453fcb
|
[19]
|
Justice, A.C., Freiberg, M.S., Tracy, R., Kuller, L., Tate, J.P., Goetz, M.B., Fiellin, D.A., Vanasse, G.J., Butt, A.A., Rodriguez-Barradas, M.C., et al. and VACS Project Team (2012) Does an Index Composed of clinical Data Reflect Effects of Inflammation, Coagulation, and Monocyte Activation on Mortality among Those Aging with HIV? Clinical Infectious Diseases, 54, 984-994. http://dx.doi.org/10.1093/cid/cir989
|
[20]
|
Baker, J., Quick, H., Hullsiek, K.H., Tracy, R., Duprez, D., Henry, K. and Neaton, J.D. (2010) Interleukin-6 and D-Dimer Levels Are Associated with Vascular Dysfunction in Patients with Untreated HIV Infection. HIV Medicine, 11, 608-609. http://dx.doi.org/10.1111/j.1468-1293.2010.00835.x
|
[21]
|
Hileman, C.O., Longenecker, C.T., Carman, T.L., Milne, G.L., Labbato, D.E.,Storer, N.J., White, C.A. and McComsey, G.A. (2012) Elevated D-Dimer Isindependently Associated with Endothelial Dysfunction: A Cross-Sectional Study in HIV-Infected Adults on Antiretroviral Therapy. Antiviral Therapy, 17, 1345-1349. http://dx.doi.org/10.3851/IMP2297
|
[22]
|
Bissuel, F., Berruyer, M., Causse, X., Dechavanne, M. and Trepo, C. (1992) Acquired Protein S Deficiency: Correlation with Advanced Disease in HIV-1-Infectedpatients. Journal of Acquired Immune Deficiency Syndromes, 5, 484-489.
|
[23]
|
Lijfering, W.M., Sprenger, H.G., Georg, R.R., van der Meulen, P.A. and van derMeer, J. (2008) Relationship between Progression to AIDS and Thrombophilic Abnormalities in HIV Infection. Clinical Chemistry, 54, 1226-1233. http://dx.doi.org/10.1373/clinchem.2008.103614
|
[24]
|
Shen, Y.M. and Frenkel, E.P. (2004) Thrombosis and a Hypercoagulable State in HIV-Infected Patients. Clinical and Applied Thrombosis/Hemostasis, 10, 277-280. http://dx.doi.org/10.1177/107602960401000311
|
[25]
|
Calmy, A., Gayet-Ageron, A., Montecucco, F., Nguyen, A., Mach, F., et al. (2009) HIV Increases Markers of Cardiovascular Risk: Results from a Randomized, Treatment Interruption Trial. AIDS, 23, 929-939. http://dx.doi.org/10.1097/QAD.0b013e32832995fa
|
[26]
|
Neuhaus, J., et al. (2010) Markers of Inflammation, Coagulation, and Renal Function Are Elevated in Adult with HIV Infection. The Journal of Infectious Diseases, 201, 1788-1795. http://dx.doi.org/10.1086/652749
|
[27]
|
Fultz, S.L., McGinnis, K.A., Skanderson, M., Ragni, M.V. and Justice, A.C. (2004) Association of Venous Thromboembolism with Human Immunodeficiency Virus and Mortality in Veterans. American Journal of Medicine, 116, 420-423. http://dx.doi.org/10.1016/j.amjmed.2003.10.011
|
[28]
|
Kuller, L.H., Tracy, R., Belloso, W., De Wit, S., Drummond, F., et al. (2008) Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection. PLoS Medicine, 5, e203. http://dx.doi.org/10.1371/journal.pmed.0050203
|
[29]
|
DiNisio, M., Squizzato, A., Rutjes, A.W.S., Buller, H.R., Zwinderman, A.H. and Bossuyt, P.M.M. (2007) Diagnostic Accuracy of D-Dimer Test for Exclusion of Venous Thromboembolism: A Systematic Review. Journal of Thrombosis and Haemostasis, 5, 296-304. http://dx.doi.org/10.1111/j.1538-7836.2007.02328.x
|
[30]
|
Cosmi, B., Legnani, C., Cini, M., Guazzaloca, G. and Palareti, G. (2011) D-Dimer and Residual Vein Obstruction as Risk Factors for Recurrence during and after Anticoagulation Withdrawal in Patients with a First Episode of Provoked Deep-Vein Thrombosis. Journal of Thrombosis and Haemostasis, 105, 837-845. http://dx.doi.org/10.1160/TH10-08-0559
|
[31]
|
Ay, C., Dunkler, D., Quehenberger, P., Marosi, C., Zielinski, C., Chiriac, A.-L. and Pabinger, I. Prediction of Venous Thromboembolism in Cancer Patients. Blood, 116, 5377-5382. http://dx.doi.org/10.1182/blood-2010-02-270116
|
[32]
|
Baker, J.V., Neuhaus, J., Duprez, D., Kuller, L.H., Tracy, R., et al. (2011) Changes in Inflammatory and Coagulation Biomarkers: A Randomized Comparison of Immediate versus Deferred Antiretroviral Therapy in Patients with HIV Infection. Journal of Acquired Immune Deficiency Syndromes, 56, 36-13. http://dx.doi.org/10.1097/QAI.0b013e3181f7f61a
|
[33]
|
Harper, P.L., Theakston, E., Ahmed, J. and Ockelford, P. (2007) D-Dimer Concentration Increases with Age Reducing the Clinical Value of the D-Dimer Assay in the Elderly. Internal Medicine Journal, 37, 607-613. http://dx.doi.org/10.1111/j.1445-5994.2007.01388.x
|
[34]
|
Strategies for Management of Antiretroviral Therapy (SMART) Study Group (2006) CD4+ Count-Guided Interruption of Antiretroviral Treatment. New England Journal of Medicine, 355, 2283-2296. http://dx.doi.org/10.1056/NEJMoa062360
|