Author(s)

Wafa Hamid Haroun Himmat, Nasr Eldeen Ali Mohammed Gaufri

Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan.

Background: The elevation of plasma D-dimer levels is fully described and associated with the increase of the mortality of patients with HIV. The present study was aimed to estimate and assess the plasma D-dimer levels in HIV patient. Material and Methods: A case control study done in May 2015. A total of 100 subjects were enrolled in this study; 50 were patients professionally diagnosed by HIV; 25 (50%) were males and 25 (50%) were females; their mean age is 35 years. Further 50 normal healthy individuals as normal control group: their gender and age were matched with patient groups. The platelets poor plasma (PPP) was immediately prepared from citrated blood, then the plasma D-dimer level was measured using (MISPA-i₂ Reagent) Switzerland. Data were analyzed using statistical packing for social sciences program (SPSS) 20. Results: The D-dimer levels was significantly higher in patient with HIV compared with the normal healthy control group (Mean and STD 502.2 ± 287.8 vs 251.8 ± 152.7 P. value 0.01). Conclusion: The D-dimer level was significantly higher in patient with HIV compared with those in normal healthy control group.

HIV, AIDS, D-Dimer, Sudan

Himmat, W. and Gaufri, N. (2016) Estimation and Assessment of Plasma D-Dimer Levels in HIV Patients. Journal of Biosciences and Medicines, 4, 1-5. doi: 10.4236/jbm.2016.410001.