TITLE:
Determinants of adverse pregnancy outcomes among Sickle Cell Disease deliveries at a tertiary hospital in Tanzania from 1999 to 2011
AUTHORS:
Projestine Muganyizi
KEYWORDS:
Sickle Cell Disease; Pregnancy; Adverse Outcome; Tanzania
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.3 No.6,
July
17,
2013
ABSTRACT:
Purpose:
Sub-Saharan Africa has the world’s largest burden of Sickle Cell Disease (SCD),
but due to poor care of SCD in childhood most do not reach reproductive ages.
Consequently, due to sporadic cases of SCD in pregnancy, there has been little
research attention to the problem in this sub region. This is one of the
largest study series of SCD deliveries in Sub-Saharan Africa that aimed to
establish the incidence and determinants of adverse pregnancy outcomes. Methods:
Data of all deliveries from 1999 to 2011 at Muhimbili National Hospital (MNH)
in Tanzania were analyzed. Deliveries of SCD were obtained and categorized according
to presence or absence of adverse pregnancy outcomes based on set composite
criteria. Using IBM SPSS statistics version 19, bivariate and multivariate
logistic regression analyses were done to determine factors that were independently
associated with adverse pregnancy outcomes. Statistics with p-value