TITLE:
Epidemiological and Therapeutic Aspects of SARS-CoV-2 Disease in the Resuscitation Department of the Omar BONGO ONDIMBA Army Training Hospital
AUTHORS:
Raphaël Okoue Ondo, Ghislain Edjo Nkilly, Arthur Ifoudji Makao, Sarah Dondyas Orema, Vanessa Sagbo Ada, Wilfried Mouiry Bivigou, Ulysse Mayegue Anani, Jean-Marcel Mandji Lawson
KEYWORDS:
SARS-CoV-2, Epidemiology, Resuscitation, Gabon
JOURNAL NAME:
Open Journal of Emergency Medicine,
Vol.13 No.2,
June
6,
2025
ABSTRACT: Introduction: The SARS-CoV-2 pandemic is a major public health problem worldwide. The most severe cases require hospitalization in intensive care units. The main objective of this study was to describe the epidemiological and therapeutic data of patients hospitalized in the Anesthesia-Resuscitation Department of the Omar BONGO ONDIMBA Army Training Hospital. Patients and Method: Descriptive, retrospective, monocentric study of patients admitted to the Department of Anaesthesia-Resuscitation for SARS-CoV-2 infection, in the period from December 2020 to December 2022. Results: 107 patients were enrolled, with a predominance of males (sex ratio 1.1). The mean age was 57.45 ± 15.93 years. The most frequent comorbidities were hypertension (52.3%) and diabetes (29.0%). The most frequent clinical signs were fatigue 81.3%, cough 42.10%, and fever 15.89%. Respiratory distress was predominant in 93.86% of cases. On admission, 79.47% of patients showed polypnea and 89.72% desaturation. ARDS was confirmed in 78.57% of patients with gasometry. RT-PCR was positive in 75.76% of cases. Chest CT scans were performed in 85.98% of cases, with ground-glass lesions in 70.65%. Management was based on Gabonese national recommendations. All patients received dual antibiotic therapy, 93.58% corticosteroids and 85.05% curative-dose heparin therapy. Vasopressor amines were required in 3.74% of patients, and 5.61% benefited from extra-renal purification. The average length of stay was 5.93 ± 4.95 days, with extremes of 1 and 32 days. The outcome was unfavorable in 43.93% of patients. Conclusion: Knowledge of the profiles of SARS-CoV-2 infection will help improve patient management. A multisite study will provide a clearer picture and confirm the risk factors associated with disease severity.