TITLE:
The Effect of Mild-Pressure Hyperbaric Therapy (Oasis O2) on Fatigue and Oxidative Stress
AUTHORS:
Sungdo Kim, Takehiko Yukishita, Keiko Lee, Shinichi Yokota, Ken Nakata, Daichi Suzuki, Hiroyuki Kobayashi
KEYWORDS:
Mild-Pressure Hyperbaric Chambe; Oxidative Stress; Free Radicals; Reactive Oxygen Species (ROS)
JOURNAL NAME:
Health,
Vol.3 No.7,
July
18,
2011
ABSTRACT: Mild-pressure hyperbaric therapy (mHBT) has become increasingly popular among elite athletes and most recently among the general public yet there is very little scientific underpinnings on its therapeutic use. In this study, fifteen healthy volunteers (8 men, 7 women, mean age 29.7 ± 8.1 years) were exposed to 1.3 atmospheres absolute (ATA) for 40 minutes in a mild hyperbaric chamber called “Oasis O2” to determine the effect of ambient air at 1.3 ATA on oxidative stress, antioxidant potential, fatigue, and blood chemistry. Reactive oxygen metabolites (ROMs), an index of oxidative stress, significantly reduced by 11% (p = 0.006), while biological antioxidant potential (BAP), an index of antioxidant capacity, did not show a significant change (p = 0.749). WBC count significantly reduced by 10.4% (p = 0.005) whereas WBC differential did not show a marked change. The mean visual analog scale (VAS) score for fatigue significantly decreased from 5.0 to 2.1 (p