TITLE:
Carcinosarcoma of the Hypopharynx—A Rare Entity with Unique Surgical Procedure
AUTHORS:
Sangeet Kumar Agarwal, Satinder Singh, Shalabh Sharma, Asish Kumar Lahiri
KEYWORDS:
Carcinosarcoma; PET Scan; LASER
JOURNAL NAME:
International Journal of Otolaryngology and Head & Neck Surgery,
Vol.2 No.6,
November
11,
2013
ABSTRACT:
Background: Carcinosarcoma of hypopharynx is a rare neoplasm with both
malignant epithelial and mesenchymal components. They are highly aggressive in
nature with controversial histogenesis. To our knowledge, there
is no case reported of carcinosarcoma of hypopharynx managed with wide LASER
excision and modified radical neck dissection followed by chemoradiation. Method and Result: 42-year-old male
presented complaints of foreign body sensation in throat, and difficulty
in swallowing and hoarseness for 4 months. On examination, a large smooth
globular mass filling the supraglottis obscuring the view of endolarynx was
noted and right side level-II cervical lymphadenopathy was found. CECT neck
revealed a large hypopharyngeal mass abutting the supraglottis.
Microlaryngoscopic biopsy was reported as high grade carcinosarcoma and PET
scan was done after 1 week which revealed no any distant metastasis. The patient
was taken for transoral pulsed carbon dioxide LASER excision with modified
radical neck dissection, and postoperative chemoradiation was done and
after two years of closed follow-up MRI was done which revealed no disease and the patient
is absolutely free of disease till now. Conclusion: It was a rare case which was managed with complete LASER excision with neck
dissection and postoperative chemoradiation and the patient is
absolutely free of disease till now after 2 years of follow-up.