TITLE:
Relationship between peripheral arterial disease, carotid intima-media thickness and C-reactive protein in elderly diabetic patients
AUTHORS:
Moatassem Salah Amer, Samia Ahmed Abdul-Rahman, Wafaa Mostafa Abd-El Gawad, Ibrahim Ahmad Abdel Aal, Ahmad Abdel Khalek Abdel Razek Mohamed, Wessam El-Huseiny Moustafa Abdel Wahab
KEYWORDS:
Peripheral Arterial Disease; Carotid Intima-Media Thickness; Ankle Brachial Index; C-Reactive Protein; Elderly
JOURNAL NAME:
Advances in Aging Research,
Vol.2 No.4,
October
9,
2013
ABSTRACT: Purpose: To study the association between carotid intima media thickness (CIMT) and high sensitivity CRP (hs-CRP) level as markers for PAD in elderly patients with DM. Subjects: A case-control study on 90 participants aged 60 years and older divided into 60 cases (30 patients with DM alone and 30 patients with DM and comorbidities) and 30 healthy controls. All were assessed by measuring CIMT, ankle brachial index (AB), and markers for cardiovascular disease such as high-sensitivity CRP (hs-CRP), total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL), and low density lipoprotein (LDL). Results: hs-CRP levels showed statistically significant difference being highest among patients with DM and comorbidities and lowest among controls (P