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has been cited by the following article:

• TITLE: The validity of predicting prognosis by the number of lymph node metastases in node-positive colon cancer

  AUTHORS: Kiichi Sugimoto, Masaya Kawai, Kazuhiro Takehara, Yoshihiko Tashiro, Shinya Munakata, Kiichi Nagayasu, Koichiro Niwa, Shun Ishiyama, Hiromitsu Komiyama, Makoto Takahashi, Yutaka Kojima, Michitoshi Goto, Yuichi Tomiki, Kazuhiro Sakamoto

  KEYWORDS: Colon Cancer; Lymph Node Metastasis; Stage Classification; TNM Classification; Prognostic Factors

  JOURNAL NAME: Open Journal of Gastroenterology, Vol.3 No.4, August 1, 2013

  ABSTRACT: Background: We examined the possibility of predicting prognosis by the number of lymph node metastases. Methods: Two hundred and forty nine patients with lymph node metastases who underwent curative surgery for colon cancer were enrolled in this study. We calculated cancer-specific survival according to the number of lymph node metastases. Results: There was a tendency toward better rates of cancer-specific survivals among the patients with 1 LNM, compared with those with 2 LNM (p = 0.07). When comparing cancer-specific survival between the patients with 1, 2-3 and 4 or more lymph node metastases, cancer-specific survival was well stratified (p i.e., the patients with 1, 2 and 3 and 4 or more lymph node metastases. This study was in favor of the TNM classification in which N category is classified by the number of lymph node metastases.