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B. Z. Haznedaroglu, I. C. Haznedaroglu, S. L. Walker, H. Bilgili, H. Goker, A. Kosar, A. Aktas, O. Captug, M. Kurt, O. Ozdemir, S. Kirazli and H. C. Firat, “Ultrastructural and Morphological Analyses of the in vitro and in vivo Hemostatic Effects of Ankaferd Blood Stopper,” Clinical and Applied Thrombosis/Hemostasis, Vol. 16, No. 4, 2010, pp. 446-453. doi:10.1177/1076029609343706

has been cited by the following article:

  • TITLE: The Hemeostatic Efficacy of ANKAFERD after Excision of Full Thickness Burns: A Comparative Experimental Study in Rats

    AUTHORS: Yusuf Kenan Coban, Elif Ozerol, Kevser Tanber, Serkan Erbatur, Ahmet Hamdi Aytekin, Cemal Fırat

    KEYWORDS: Ankaferd Blood Stopper, Burn Surgery, Bleeding

    JOURNAL NAME: Surgical Science, Vol.2 No.1, January 29, 2011

    ABSTRACT: Objective: In order to evaluate the effects of Ankaferd blood stopper (ABS) on post-excisional burn wound bleeding via monitoring early blood hemoglobin level changes and to make a comparison with a standart topical treatment, a controlled experimental study was conducted. Design and Interventions: A contact burn model of full-thickness injury with 30% TBSA was used. Following the burn injury, excisions of burned areas were done at postburn 48th hour. 24 male Spraque Dawley rats were divided into control, adrenaline, ABS-solution and ABS-pad treatment groups. In control group no treatment was done for bleeding, but the other three groups had topical treatments. Samples were taken at the begining of the study, just before and 1 hour after the burn wound excisions for measurement of haemoglobine (Hb) levels and additionally the external bleeding amounts were measured by weighing the topical pads. Measurements and main results: Baseline Hb levels of control, adrenaline, ABS-solution and ABS-pad treatment groups were 15.06 ± 0,83, 15,82 ± 0.83, 16.23 ± 1.14 and 15.16 ± 1.46 respectively. At the 48th hour of postburn injury, the Hb levels of these groups were 13.82 ± 0.58, 13.68 ± 1.26, 13.79 ± 0.90 and 13.57 ± 0.89. Mean blood loss amounts (ml) after burn wound excisions in groups were 1.44 ± 0.26, 0.65 ± 0.07, 0.53 ± 0.08 and 0.44 ± 0.09. Conclusions: ABS was found to be as effective as topical adrenaline on reducing excisional bleeding in the experimental burn injury model.