Wang, J., Nasser, N., Kwon and Cho, M.Y. (1992) Tissue bioelectrode for organic-phase enzymatic assays, Analytical chimica Acta, 2649, 7-12. doi:10.1016/0003-2670(92)85290-M

has been cited by the following article:

• TITLE: Analytical solution of the concentration and current in the electoenzymatic processes involved in a PPO-rotating-disk-bioelectrode

  AUTHORS: Govindhan. Varadharajan, Lakshmanan. Rajendran

  KEYWORDS: Mathematical Model; Polyphenol Oxidase; Steady-State; Homotopy Perturbation Method; Simulation

  JOURNAL NAME: Natural Science, Vol.3 No.1, January 29, 2011

  ABSTRACT: A mathematical model for electroenzymatic process of a rotating-disk-bioelectrode in which polyphenol oxidase occurs for all values of concentration of catechol substrate is presented. The model is based on system of reaction-diffusion equations containing a non-linear term related to Michaelis-Menten kinetics of the enzymatic reaction. Approximate analytical method (He’s Homotopy perturbation method) is used to solve the non-linear differential equations that describe the diffusion coupled with a Michaelis-Menten kinetics law. Closed analytical expressions for substrate concentration, product concentration and corresponding current response have been derived for all values of parameter using perturbation method. These results are compared with simulation results and are found to be in good agreement. The obtained results are valid for the whole solution domain.