TITLE:
Morphometrical findings among dysplasias of oral, cervical and bronchial regions
AUTHORS:
Kayo Kuyama, Takashi Matsumoto, Miyuki Morikawa, Akira Fukatsu, Mana Ichimura, Masanobu Wakami, Masahiko Fukumoto, Taku Kato, Hirotsugu Yamamoto
KEYWORDS:
Exfoliative Cytology; Dysplasia; Oral Mucosa; Cervix; Bronchus
JOURNAL NAME:
Open Journal of Stomatology,
Vol.3 No.2,
May
28,
2013
ABSTRACT:
The purpose of this study was to compare among
dysplasia of oral, uterine cervix and bronchus. Using a computer
cytomorphometry cell measurement program, the study was based on a
retrospective review of smear cases diagnosed with dysplasia of oral, bronchial
and uterine cervix, from 2002 to 2010. For 50 - 70 cells from each lesion,
nuclear (N) and cytoplasm (C) variables were assessed: area (A), diameter (D),
irregularity (I), stain brightness and granularity. NA and ND were highest in
OSCC and higher according to dysplastic grading. By contrast, CA and CD were lowest
in severe dysplasia. The significant difference of N/C ratio was observed among
OSCC to inflammation, mild and moderate dysplasias (p