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G. William and M. D. Schucany, “Wegener’s Granulomatosis Presenting as a Large Solitary Cavitary Mass,” Proceedings of Baylor University Medical Center, Vol. 23, No. 2, 2010, pp. 171-172.

has been cited by the following article:

  • TITLE: Wegener’s Granulomatosis Presenting with Bilateral Excavated Nodules

    AUTHORS: Emna Braham, Hajer Racil, Houda Ben Rejeb, Moncef Hamdane, Abdellatif Chabou, Faouzi El Mezni

    KEYWORDS: Vasculitis; Wegener; Pathology; Lung; Granulomatous Inflammation

    JOURNAL NAME: Open Journal of Pathology, Vol.2 No.2, April 20, 2012

    ABSTRACT: Wegener’s granulomatosis (WG) is a systemic inflammatory disease whose histopathologic features often include necrosis, granuloma formation, and vasculitis of small-to-medium-sized vessels. We report a new case of Wegener’s granulomatosis occurring in a 41-year-old man who was admitted for respiratory symptoms, fever, asthenia, night sweats and weight loss since one month. Chest X-ray and computed tomography showed multiple bilateral pulmonary excavated lesions. A trransparietal lung biopsy was performed. Histological examination showed an area of necrosis, surrounded by a palisade of histiocytes. Some of the histiocytes were multinucleated and formed true granulomas within the wall of the adjacent pulmonary artery. Serology was strongly positive for ANCA. A diagnosis of Wegener granulomatosis was conducted and the patient was started on cyclophosphamide and methylprednisolone as an initial treatment, with a favorable evolution.