TITLE:
Cure of Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System: A Case Report
AUTHORS:
Chengming Xu, Congyan Wu, Meiqing Lou, Yaodong Zhao
KEYWORDS:
Atypical Teratoid/Rhabdoid Tumor, Case Report
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.9 No.1,
December
31,
2019
ABSTRACT: Atypical teratoid/rhabdoid tumor (AT/RT) is an embryonic central nervous system tumor. It has a low incidence with a high degree of malignancy and a poor prognosis. Five years ago, we successfully treated a child with AT/RT. Treatment comprised total tumor resection, 6 MV X 3D conformal radiotherapy (DT: 36Gy/18FX) and six courses of chemotherapy, including teniposide 25 mg (qd × 5d), ACNU 25 mg (qd × 1d), vincristine 1 mg (qd × 1d). There was no tumor recurrence after 5 years of follow-up. We adjusted the previous AT/RT regimen to make it more suitable for the individual treatment of this patient, and now the patient has achieved a cure. So we think this regimen is effective and it is worthy of recommendation.