TITLE:
Tubercular Uveitis in the Event of HIV Infection about a Case
AUTHORS:
Abdramane Traoré, Hamsatou Cisse, Nagou Tolo, Djenebou Traoré, Condé Lassana, Assétou Soukho Kaya, Abasse Sanogo, Bréhima B. Berthé, Ibrahima Amadou Dembélé, Mahamadou Saliou, Djibril Sy, Nanco Doumbia, Sekou Mamadou Cissé, Boubacar Zana Cisse, Mamadou Dembélé, Abdel Kader Traoré, Hamar Alassane Traoré
KEYWORDS:
Tucerculose/Uveitis
JOURNAL NAME:
Journal of Tuberculosis Research,
Vol.7 No.4,
December
24,
2019
ABSTRACT: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. This disease is the second leading cause of infectious mortality in the world after infection with the human immunodeficiency virus. We report a case of multifocal tuberculosis with neuromuscular and ocular localization in an HIV-1 immunosuppressed patient in clinical and virological failure following therapeutic discontinuation due to non-compliance. This is a 43-year-old immunocompromised HIV1 patient with a history of cerebral toxoplasmosis in 2016 who consulted for right hemiplegia. These symptoms would go back to about 3 days marked by a deficit of progressive installation of the right hemicorps preceded by diffuse headaches, of moderate intensity without triggering factor radiating to the eyes associated with an intermittent fever with periods of spontaneous remissions, night sweats and chills, non-selective anorexia, non-increasing physical asthenia and unquantified weight loss. Management was 8-month antituberculous treatment, combining the first two months isoniazid (INH), rifampicin (RMP), pyrazinamide (PZN) and ethambutol (EMB), then the next 6 months (INH) and rifampicin (RMP). The reintroduction of the same antiretroviral protocol and a reinforcement of the therapeutic education made it possible to observe a decrease of the viral load. Treatment of ocular involvement was instituted with Timosol 1 drop in the eyes morning and evening and Diclocid 1 mg/ml: 1 drop in the eyes in the morning.