Yokoyama, T., Yoshida, D., Mori, H., Okabe, M., Shervani, Z., Taga, K., Yamamoto, Y., Sumino, A., Dewa, T., Nango, M. and Yamamoto, M. (2016) Morphological Observation of Specific Condensation Effect of Cholesterol on Dipalmitoyl Phosphatidyl Choline (DPPC) Monolayer by Dropping Method. Journal of Biophysical Chemistry, 7, 98-109.
https://doi.org/10.4236/jbpc.2016.74009

has been cited by the following article:

• TITLE: Structural Change in Dimyristoyl Phosphatidyl Choline (DMPC) Molecule Alkyl Chains on the Addition of Cholesterol to DMPC Monolayer: Specific Addition Effect of Cholesterol

  AUTHORS: Daiki Ito, Takanari Ikeda, Keijiro Taga, Yasushi Yamamoto, Zameer Shervani, Masato Yamamoto

  KEYWORDS: Dimyristoyl Phosphatidyl Choline (DMPC), Cholesterol, Surface Tension Measurement (STm), Brewster Angle Microscopy (BAM), Infrared External Reflection Microscopy (IERS), Structural Transition

  JOURNAL NAME: Journal of Biophysical Chemistry, Vol.10 No.2, May 28, 2019

  ABSTRACT: We have investigated the morphology of dimyristoyl phosphatidyl choline (DMPC)—cholesterol mixed monolayer formed on the water surface by dropping method using surface tension measurement (STm), Brewster angle microscopy (BAM), and infrared external reflection spectroscopy (IERS). STm results showed negative deviation of the limiting molecular area (A0) of cholesterol occurred when cholesterol was added to the DMPC monolayer. BAM images showed the expandable DMPC monolayer changed to the condensed rigid monolayer at more than cholesterol mole fraction (xChol) 0.4. IERS recordings showed that the addition of cholesterol at xChol = 0.4 occurred structural change from gauche- to trans- conformation of two DMPC molecule alkyl chains. From these results, it is found that cholesterol molecule has specific properties that cause structural transition of DMPC molecule alkyl chains.