TITLE:
New Insights into the Discovery of Novel Drugs to Treat Human Pulmonary Adenocarcinoma
AUTHORS:
Yu Wang, Haishan Zhang, Yingxin Chen, Lining Wang
KEYWORDS:
Cisplatin, Docetaxel, Pemetrexed, Adenocarcinoma, In Vitro, In Vivo, Clinical Trial
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.10 No.2,
February
21,
2019
ABSTRACT: Lung cancer is one of the most prevalent cancers in the world. A cisplatin-based chemotherapy regimen is commonly used to major
patients who have adenocarcinoma. Because of the limited remission rate, many
patients need receive second-line treatment after receiving first-line
chemotherapy. Drug screenings carried out currently are mainly from single phase. In consideration of systemic
treatment, evaluation of a novel drug candidate from the point of view of first-line
and second-line treatment is supposed to be important in the process of drug
screening. In this review, we propose a flow of searching for new drugs, which
is tailored to accommodate to first-line and second-line treatment in clinic.