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has been cited by the following article:

• TITLE: Separation and Purification of Ursolic Acid from Cynomorium songaricum Exacts with Macroporous Resins

  AUTHORS: Xifeng Zhang, Wangxu Hou, Xue Zheng

  KEYWORDS: Ursolic Acid, Macroporous Resins, Cynomorium songaricum Rupr

  JOURNAL NAME: Open Access Library Journal, Vol.5 No.5, May 24, 2018

  ABSTRACT: Enrichment and purification of ursolic acid from Cynomorium songaricum exacts were studied using five macroporous resins. The static tests indicated that D101 resin was appropriate and its adsorption data were well fitted to the Langmuir and Freundlich isotherms. To optimize the separation process, dynamic adsorption and desorption tests were carried out. The optimal adsorption parameters were initial concentrations in sample solution of 3.8 mg/mL, pH of 6.0, sample loading amount of 5 BV, flow rate of 2 BV/h, and temperature of 25℃. The optimal desorption parameters were 70% ethanol 5 BV, then 80% ethanol 10 BV, and flow rate of 2 BV/h. After one run treatment with AB-8 resin, the content of total flavonoids in the product increased from 9.83% to 67.8%, and the recovery yield was 84.02%. The results showed that AB-8 resin revealed a good ability to enrichment total flavonoids from Cynomorium songaricum, and the method can be referenced for the enrichment of total flavonoids from other materials.