TITLE:
Pineapple Juice as a Natural Catalyst: An Excellent Catalyst for Biginelli Reaction
AUTHORS:
Suresh Patil, Swati D. Jadhav, Sanjeevani Y. Mane
KEYWORDS:
Biginelli, Natural Catalyst, Pineapple Juice, Dihydropyrimidinone
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.1 No.3,
September
28,
2011
ABSTRACT: An efficient and greener synthesis of a series of dihydropyrimidinone (DHPMs) derivatives were accomplished via three-component one-pot cyclocondensation between substituted aryl aldehydes, diketone/ke- toester and urea. This solvent free approach is totally nonpolluting having several advantages such as shorter reaction time, mild reaction conditions, simple workup and reduced environmental impact.