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Hsu, K.-Y., Lin, J.-R., Lin, M.-S., Chen, W., Chen, Y.-J. and Yan, Y.-H. (2013) The Modified Medical Research Council Dyspnoea Scale Is a Good Indicator of Health-Related Quality of Life in Patients with Chronic Obstructive Pulmonary Disease. Singapore Medical Journal, 54, 321-327.
https://doi.org/10.11622/smedj.2013125

has been cited by the following article:

  • TITLE: Correlation of Self-Reported Breathlessness with Post Exercise Dyspnea in Obesity

    AUTHORS: Michael Agustin, Hong Chang, John Unterborn, Augustine Andoh-Duku

    KEYWORDS: Obesity, Dyspnea, Dyspnea Questionnaire, mMRC, Validity Study

    JOURNAL NAME: Open Journal of Respiratory Diseases, Vol.7 No.4, November 24, 2017

    ABSTRACT: Background: Dyspnea in obesity is common and dyspnea questionnaires are mostly validated for chronic respiratory diseases. The study aims to assess how modified Medical Research Council (mMRC) dyspnea scale correlates with post exercise dyspnea Borg scale in 6-minute walk test of the obese population. Methods: We performed a retrospective observational study on 342 obese patients with 6 MWT tests from February 2008 to November 2014 at a single tertiary hospital. Linear regression analysis was used to assess the relationship between mMRC and Borg dyspnea score. Fractional polynomial regression was used to analyze the relationship of mMRC and Borg scores with BMI. Results: MMRC dyspnea score was a strong predictor of post exercise dyspnea Borg score in the obese population in a univariate regression model (coefficient = 0.764, p ≤ 0.001). When adjusted to age, BMI, 6 MWT distance and PFT parameters in a multivariate regression model, the relationship remained statistically significant (coefficient = 0.587, p ≤ 0.001). The relationship was stronger in obese group with no airflow obstruction. Conclusion: In obese population, pre-exercise mMRC dyspnea score correlates significantly with post exercise dyspnea Borg score regardless of airflow obstruction. This is the first validity study regarding mMRC scale in assessing dyspnea in the obese population.