TITLE:
Effects of Gaseous Drinks in Wistar Rats Esophagus
AUTHORS:
Thiago Dornelas de Oliveira, Marcelli Eliotério Gaspar, Larissa Menezes Viana Braga, Joice Meire Rodrigues, Rebeca Nogueira Falcão Santos, Suelen Gaudino Moura, Nayara Barbosa Bicalho, Lamara Laguardia Valente Rocha, Daniel Almeida da Costa, Marcus Vinicius de Mello Pinto
KEYWORDS:
Soft Drinks Consumption, Inflammation, Carbonate Beverages
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.5 No.5,
May
26,
2017
ABSTRACT: The consumption of beverages and processed foods, mainly soft drinks, has been incorporated into the usual diet of children, adolescents and adults frequently in recent years. The present study aimed to study the effects of carbonated drinks on Wistar rats, based on the macroscopic and histological morphology of the esophagus. Fifteen Wistar rats were divided into three groups: control group; group fed with ration and cola-type refrigerant ad libitum and group fed with ration and gas industrialized water ad libitum, for a trial period of 90 days. For histopathology and morphology, the esophagus was removed, prepared in slides and stained with hematoxylineosin. Images of the sections were captured for analysis and classification of the inflammatory infiltrate. For morphometry, ten grid fields of 100 points were evaluated in the 40x eyepiece, totaling 3000 points per animal. The results demonstrate that the refrigerant treatment induced the following structural changes in the rats: significant reduction of weight in relation to the control group; inflammatory infiltrate predominantly diffuse mild to moderate and tissue edema. The rats treated with carbonated water had similar results to the control, besides signs of healing and tissue repair.