Article citationsMore>>
Tiwaria, R.K., Singha, D., Singha, J., Chhillarb, A.K., Chandraa, R. and Vermaa, A.K., (2006) Synthesis, antibacterial activity and QSAR studies of 1, 2-disubstituted-
6,7-dmethoxy-1, 2, 3, 4-tetrahydroisoquinolines, Europe
Journal Medicine Chemical, 41, 40-49.
doi:10.1016/j.ejmech.2005.10.010
has been cited by the following article:
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TITLE:
Reactivity of 1-methylisoquinoline synthesis of pyrazolyl triazoloisoquinoline and thia-diazolyl isoquinoline derivatives
AUTHORS:
Hamdi M Hassaneen, Huwaida M. E Hassaneen, Yasmin Sh Mohammed
KEYWORDS:
[1, 2, 4]Triazolo[3, 4-a]isoquinolines; Enaminones; Hydrazonoyl Halides; Cycloaddition Reactions; Chitosan; Thioanilides; [1, 3, 4]Thiadiazolylisoquinoline Derivatives
JOURNAL NAME:
Natural Science,
Vol.3 No.8,
August
3,
2011
ABSTRACT: The reaction of 1-methylisoquinoline 1 with hy-drazonoyl halides 2 in ethanol in the presence of chitosan under microwave irradiation affords triazoloisoquinoline 4. Product 4 reacts with dimethylformamide-dimethylacetal to give ena- minones 7 which react with hydrazonoyl halides to give pyrazolyl triazoloisoquinoline 13. Also, 1-methylisoquinoline 1 reacts with arylisothio-cyanate to give thioanilide 15 which reacts with hydrazonoyl halides to give the corresponding thiadiazolyl isoquinoline derivatives 20, 24.
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