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has been cited by the following article:

• TITLE: Comparison of GeneXpert MTB/RIF Assay in Broncho Alveolar Lavage and Gastric Lavage Samples

  AUTHORS: Ravi Mahat, Nadeem Rizvi, Nausheen Saifullah, Madiha Tawfik, Ashok Kumar

  KEYWORDS: Mycobacterium tuberculosis Complex, Rifampicin Resistance, Bronchoscopy, TB Suspects

  JOURNAL NAME: Advances in Infectious Diseases, Vol.6 No.3, September 5, 2016

  ABSTRACT: Objective: To compare the yield from Gastric lavage (GL) and Broncho alveolar lavage (BAL) samples in adult patients suspected case of Tuberculosis but not producing sputum. Methodology: 80 adults with suspected case of tuberculosis but not producing sputum were recruited. 72 patients were then subjected to one gastric lavage followed by Broncho-alveolar lavage in the same morning. The collected samples were subjected toGeneXpert MTB/RIF assay. Result: Of the 72 patients samples, the mean age was 38.6 years. 41 (56.9%) were male and 31 (43.1%) were female. History of TB contact was present in 25 (34.7%) patients. 37 (51.4%) patients had GeneXpert MTB/RIF positive on BAL and/or GL samples. The GeneXpert MTB/RIF of BAL fluid was positive on 35(48.6%), which was not significantly greater than that for specimens from GL, which was 28(38.9%) (p > 0.05). In 26 (36.1%) cases, GeneXpert MTB/RIF was positive in both BAL and GL samples. Conclusion: This study showed the yield of GeneXpert MTB/RIF in GL was comparable to BAL to detectMycobacterium tuberculosiscomplex. Patients who can’t produce sputum, GL can be a good alternative to BAL to detect Mycobacterium tuberculosiscomplex in resource poor areas and patients who do not tolerate Bronchoscopy.