TITLE:
Body Mass Index, Waist Circumference and Cut-Off Points for Metabolic Syndrome in Urban Residents in Ningxia
AUTHORS:
Jianjun Yang, Hongyan Qiu, Hongyu Li, Yuhong Zhang, Xiujuan Tao, Yanna Fan
KEYWORDS:
MS, BMI, WC, ROC Curves
JOURNAL NAME:
Open Journal of Endocrine and Metabolic Diseases,
Vol.5 No.12,
December
8,
2015
ABSTRACT: A growing number of
studies show that different countries and populations require different cut-off
points for body mass index (BMI), and waist circumference (WC) leading to
obesity. There are no data on optimal cut-off points to metabolic syndrome (MS)
among urban residents in Ningxia. Our aim is to determine the appropriate
cut-off points for BMI and WC associated with elevated prevalent MS risk among
urban residents in Ningxia. A total of 2500 urban residents in Ningxia were
examined from May 2008 to March 2009 in a community-based cross-sectional
study. Height, body weight, waist circumference and hip circumference were
measured to calculate BMI. Fasting blood glucose (FBG), plasma levels of
triglyceride (TG), total cholesterol (TC), and high-density lipoprotein
cholesterol (HDL-C) were examined using a blood glucose meter and the chromatographic
enzyme method. BMI and WC were measured to assess overweight or obesity. Of
these, 301 subjects were chosen according to metabolic syndrome diagnosis
standards to form the case group. The control group comprised 301 healthy
people without diabetes, hypertension, hyperlipemia, coronary heart disease,
cerebrovascular disease, malignant tumors or chronic infections. Logistic
regression and receiver-operating characteristic (ROC) curve analyses were used
to determine optimal cut-off points for BMI and WC in relation to the area
under the curve (AUC), sensitivity and specificity. The optimal cut-off points
for male and female respectively were 24.78 kg/m2(sensitivity = 0.879, specificity =
0.648) and 24.72 kg/m2(sensitivity
= 0.804, specificity = 0.767) for BMI, 85.95 cm (sensitivity = 0.701,
specificity = 0.641) and 78.25 cm (sensitivity = 0.804, specificity = 0.528)
for WC. Urban residents in Ningxia were at high risk of MS, and the cut-off
points for BMI and WC were lower than the data currently recommended in Asian
population.