TITLE:
Cancer and Germ Cells
AUTHORS:
Elizabeth Jeya Vardhini Samuel, Joseph Vimal, Nagarajan Natarajan, Sivakumar Periasamy, Sanjoy George, Gouthaman Thiruvenkadam
KEYWORDS:
Smashed Fragmentation of Germ Cells, Reduced Endogenous Estrogen, Germ Cell Replant Effect, Defaulted Genomic Repertoire, Metabolic Syndrome, Two Subsets of People with, without Contraception
JOURNAL NAME:
Open Journal of Preventive Medicine,
Vol.4 No.7,
July
31,
2014
ABSTRACT:
Background: Era of
contraception, abortions, [20th, 21st centuries] implemented as family welfare
schemes witnessed, increased global incidence of cancer, tumors, neoplasm and
mortality. Objectives: Altruistic association of contraception [if any], with
increasing cancer, tumor was sought after. Methods: In 2012, retrospective
analysis of, prevalence of cancer, tumor in 350 patients of 20 - 35 years, 35 -
50 years, >50 years age groups, from data collected by convenient,
stratified random sampling, from different geographical locations, between
2002-2012 and its association with presence, absence of contraception, abortion
was undertaken; simultaneously, serum estrogen levels obtained from 105 patients,
were also analyzed. From 1983-2012 clinical practice, 212 patients treated for
different types of neoplasm namely breast cancer, prostate cancer, cancer
cervix and benign prostatic hyperplasia were randomly allotted to the above 3
age groups and the data were analyzed for association with contraception status
and possible significance. Results: 6 fold increase in cancer incidence was
seen in contraceptive users among >50 years with a p value of 35 - >50
years with a p value of 50 years, in contraceptive
users with a p value of 50 years, in contraceptive users with a p value of