TITLE:
Comparative Study of Synergistic Effects of Antibiotics with Triangular Shaped Silver Nanoparticles, Synthesized Using UV-Light Irradiation, on Staphylococcus aureus and Pseudomonas aeruginosa
AUTHORS:
Sonali Saha, Mohmmad Manzar Malik, Mohmmad Shums Qureshi
KEYWORDS:
Triangular Silver Nanoparticle, Black Tea Leaves Extract, UV-Irradiation, Staphylococcus aureus, Pseudomonas aeruginosa, Ampicillin and Gentamycin
JOURNAL NAME:
Journal of Biomaterials and Nanobiotechnology,
Vol.5 No.3,
July
21,
2014
ABSTRACT:
In the present work, a comparative study of
antibacterial activity and synergistic effects of triangular silver
nanoparticles in combination with two standard antibiotics is discussed for Staphylococcus aureus and Pseudomonas aeruginosa. A green route
was developed to synthesise silver nanoparticles in which silver oxalate was
taken as precursor, black tea leaves extract as surfactant and chitin as a
stabilizing agent. A grey coloured colloidal solution of silver nanoparticles
was obtained which was characterized by using
various techniques like X-ray diffractometer (XRD), transmission electron
microscopy (TEM) and UV-visible spectroscopy. Anti-bacterial studies gave
approximately equal inhibition zones for both the combinations which states
that silver nanoparticles are to be equally effective and synergistic effects
were clearly observed in case of P.
aeruginosa.