TITLE:
Effect of cross linked sodium hyaluronate in adhesion reduction within the gynecologic surgical window
AUTHORS:
Liselotte Mettler
KEYWORDS:
Precise Laparoscopic Surgery; Adhesion Reduction with HyaCorp Endogel
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.4 No.3,
February
21,
2014
ABSTRACT:
Objectives: On an
International scale the Surgical and Clinical Adhesion Research studies (SCAR)
solidified the huge impact adhesions have on our Health Care System and the
daily complications occurring at surgical procedures because of adhesions. Study:
Retrospective file and chart review of 462 patients undergoing laparoscopic
surgery at the Department of Obstetrics and Gynecology, University Hospitals of
Schleswig Holstein, Kiel. Scientific background of HyaCorp endogel for adhesion
prevention and reduction. Observational study applying HyaCorp endogel in 125
gynecological laparoscopic surgeries for adhesion reduction: Laparoscopic Total
and subtotal hysterectomies(LTH, LSH) myomectomies and endometriosis surgeries.
Additionally the application in 30 hysteroscopic surgeries such as
polypectomies, intracavitary myomectomies and septum resections are described. Results:
50% of patients (P chronic
pelvic pain had thick fibrous adhesions. HyaCorp endogel perfectly
adheres to the tissue surface and the abdominal wall creating an anti adhesion
barrier without any side effects. At hysteroscopies the application of 1 - 2 ml
into the uterine cavity after intra-cavitary
procedures was easily performed through a 2 mm cannula applicator. Postoperatively
only in 2 cases patients had a slight pain over the first week, which did not
continue. The gel was perfectly tolerated and showed no side effects. Conclusions
and Discussion: Fibrous adhesions between pelvic organs and the pelvic side
wall during gynecological surgical procedures with laparoscopy cause severe
pain and further burden the task of the laparoscopic surgeon. The attempt to
reduce these adhesions by applying the site specific, hyaloronic acid based
barrier, HyaCorp endogel’ proved to be satisfying and helpful in this purely
observational study.