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has been cited by the following article:

• TITLE: Piericidins, Novel Quorum-Sensing Inhibitors against Chromobacterium violaceum CV026, from Streptomyces sp. TOHO-Y209 and TOHO-O348

  AUTHORS: Kazuhiro Ooka, Atsushi Fukumoto, Tomoe Yamanaka, Kanako Shimada, Ryo Ishihara, Yojiro Anzai, Fumio Kato

  KEYWORDS: Piericidin A1; 3’-Rhamnopiericidin A1; Piericidin E; Quorum-Sensing Inhibitor; Chromobacterium violaceum CV026; N-Acylhomoserinlactone

  JOURNAL NAME: Open Journal of Medicinal Chemistry, Vol.3 No.4, December 3, 2013

  ABSTRACT: Piericidin A1, 3’-rhamnopiericidin A1, and a novel compound piericidin E, a new quorum-sensing (QS) inhibitor against Chromobacterium violaceum CV026, were isolated from the culture broth of Streptomyces sp. QS is well known as a microbial signaling system and controls certain types of gene expression resulting in bioluminescence, biofilm formation, swarming motility, antibiotic biosynthesis, and virulence factor production. C. violaceum CV026 is commonly used to determine qualitative and quantitative QS activity. The structures of piericidin derivatives were characterized, and their QS activities were determined.