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https://doi.org/10.1038/ng.814

has been cited by the following article:

• TITLE: Multiple Marker Effects of Single Nucleotide Polymorphisms in Two Genes, NCAPG and PLAG1, for Carcass Weight in Japanese Black Cattle

  AUTHORS: Youji Muramatsu

  KEYWORDS: Association, Beef Cattle, Carcass Weight, Interaction, SNP

  JOURNAL NAME: Open Journal of Animal Sciences, Vol.9 No.1, January 15, 2019

  ABSTRACT: Carcass weight is an economically important trait for beef cattle breeding and markets. The previous studies detected two single nucleotide polymorphisms (SNPs) associated with carcass weight of Japanese Black: c.1326T>G in NCAPG gene and FJX_250879 in PLAG1 gene. Here, I carried out multiple marker association analysis for the two SNPs in Japanese Black population of 218 animals. The multiple marker analysis with the model including the main effects of the two SNPs and their interaction detected significant main effects of c.1326T>G and FJX_250879 and a significant interaction between the two SNPs, for carcass weight. These findings suggest the presence of inter-allelic interactions among genes affecting the variation of carcass weight. For effective marker-assisted selection for beef production, interaction between the two markers needs to be considered.