TITLE:
Multiple Marker Effects of Single Nucleotide Polymorphisms in Two Genes, NCAPG and PLAG1, for Carcass Weight in Japanese Black Cattle
AUTHORS:
Youji Muramatsu
KEYWORDS:
Association, Beef Cattle, Carcass Weight, Interaction, SNP
JOURNAL NAME:
Open Journal of Animal Sciences,
Vol.9 No.1,
January
15,
2019
ABSTRACT: Carcass weight is an economically important trait
for beef cattle breeding and markets. The previous studies detected two single
nucleotide polymorphisms (SNPs) associated with carcass weight of Japanese
Black: c.1326T>G in NCAPG gene and FJX_250879 in PLAG1 gene. Here, I carried out multiple
marker association analysis for the two SNPs in Japanese Black population of
218 animals. The multiple marker analysis with the model including the main
effects of the two SNPs and their interaction detected significant main effects
of c.1326T>G and FJX_250879 and a significant interaction
between the two SNPs, for carcass weight. These findings suggest the presence
of inter-allelic interactions among genes affecting the variation of carcass
weight. For effective marker-assisted selection for beef production,
interaction between the two markers needs to be considered.