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has been cited by the following article:

• TITLE: The Synergistic Effects Study of C-myc and C-erbB-2 in the Carcinogenesis of Gastric Carcinoma

  AUTHORS: Keqiang Wang, Jiangang Liu, Yanchao Duan, Shengyi Dongye, Jiafeng Wu, Yiren Wang, Zhenzhong Liu, Guoxin Han

  KEYWORDS: c-myc, c-erbB-2, Synergistic Effects

  JOURNAL NAME: Open Journal of Gastroenterology, Vol.7 No.12, December 28, 2017

  ABSTRACT: Objective: To study the significance of c-myc and c-erbB-2 oncogene expression in gastric cancer. Methods: 81 gastric cancer specimens were detected for c-myc and c-erbB-2 oncogene amplification using non-radioactive in situ hybridization method. Results: The amplification rates for c-myc and c-erbB-2 were 67.9% and 50.6% respectively, and there were significant correlation in the amplification of these two genes (χ2 = 7.26, P Conclusions: The amplification of c-myc and c-erbB-2 may play an important role in gastric cancer development, and these two genes may have synergistic effect.