TITLE:
Assessment of Global Fatigue in Multiple Sclerosis: A Spanish Language Version of the CGI and PGI Fatigue Scales
AUTHORS:
Steven D. Targum, Pablo Richly, Vladimiro Sinay, Daniel Goldberg-Zimring, Facundo Manes
KEYWORDS:
Reliability; Multiple Sclerosis; Spanish; Global Assessment; Fatigue; Psychometrics; Treatment Response
JOURNAL NAME:
Neuroscience and Medicine,
Vol.4 No.3,
September
10,
2013
ABSTRACT:
Background: Fatigue is often identified as weakness following muscular exertion in patients
with multiple sclerosis (MS) but may be associated with other physical,
cognitive and emotional symptoms. Objective: To develop a
Spanish language global impression of fatigue scales to evaluate symptoms of fatigue distinct from a particular disease. Methods: 50 ambulatory patients
with MS attending a clinical institute in Argentina consented to participate in
this reliability study. The Spanish language version of the Clinical and
Patient Global Impressions of Fatigue (CGI-S-F and PGI-S-F) instruments were
administered with the Massachusetts General Hospital cognitive and physical
functioning questionnaire
(MGH-CPFQ). Results: The CGI-S-F and
PGI-S-F scores were well correlated with each other (p p = ns) reflecting
borderline to mild perception of fatigue. The total MGH-CPFQ was 16.68 ± 4.32.
Both CGI-S-F and PGI-S-F measures were correlated with the MGH-CPFQ:
CGI-Severity (r = 0.632; p r = 0.717; p Conclusions: In this study, the Spanish language
versions of the CGI-S-F and PGI-S-F were reliable measures in an MS population and can be useful and easily
applied metrics in a busy clinical practice.