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Article citations


D. P. Trivedi, R. Doll and K. T. Khaw, “Effect of Four Monthly Oral Vitamin D3 (Cholecalciferol) Supplementation on Fractures and Mortality in Men and Women Living in the Community: Randomized Double Blind Controlled Trial,” British Medical Journal, Vol. 326, No. 7387, 2003, p. 469. doi:10.1136/bmj.326.7387.469

has been cited by the following article:

  • TITLE: Impact of Vitamin D Metabolism on Cardiovascular Disease

    AUTHORS: Kosaku Nitta

    KEYWORDS: Vitamin D, Mortality, Cardiovascular Disease, Hypertension, Therapeutic Option

    JOURNAL NAME: International Journal of Clinical Medicine, Vol.2 No.5, November 28, 2011

    ABSTRACT: Vitamin D is a steroid hormone that enables optimal absorption of calcium from the intestine for bone mineralization. Vitamin D receptor is present in many organs, and there has been of interest in potential functions of vitamin D, particularly in cardiovascular disease. Vitamin D deficiency is thought to be associated with an increased risk of cardiovascular disease. The mechanism by which vitamin D might improve the outcome of cardiovascular disease outcomes remains unclear. However, potential hypotheses have been proposed, including that vitamin D improves the outcome by down-regulating the renin-angiotensin-aldosterone system and by direct effects on the heart and vasculature. The estimated worldwide prevalence of vitamin D deficiency of 50% in elderly populations underlines the importance of vitamin D deficiency as a public health issue. The elderly persons have high rates of comorbid conditions, including cardiovascular disease. This article reviews changes in vitamin D level with age, the impact of vitamin D deficiency on agerelated cardiovascular disease, and different treatment options available for vitamin D deficiency in older populations.