SCIRP Mobile Website
Paper Submission

Why Us? >>

  • - Open Access
  • - Peer-reviewed
  • - Rapid publication
  • - Lifetime hosting
  • - Free indexing service
  • - Free promotion service
  • - More citations
  • - Search engine friendly

Free SCIRP Newsletters>>

Add your e-mail address to receive free newsletters from SCIRP.

 

Contact Us >>

WhatsApp  +86 18163351462(WhatsApp)
   
Paper Publishing WeChat
Book Publishing WeChat
(or Email:book@scirp.org)

Article citations

More>>

Kmiot, W.A., Youngs, D., Tudor, R., et al. (1993) Mu-cosal morphology, cell proliferation and faecal bacteri-ology in acute pouchitis. British Journal of Surgery, 80, 1445-1449. doi:10.1002/bjs.1800801132

has been cited by the following article:

  • TITLE: The pathogenesis of primary pouchitis following ileal pouch-anal anastomosis: a review of current hypotheses

    AUTHORS: Sally Bath, Christian P. Selinger, Rupert W.L. Leong

    KEYWORDS: Pouchitis; Ileo-pouch Anal Anastomosis; Pathogenesis

    JOURNAL NAME: Open Journal of Gastroenterology, Vol.1 No.2, November 17, 2011

    ABSTRACT: Primary pouchitis is a common complication of ileal pouch-anal anastomosis following proctocolectomy in patients treated for ulcerative colitis (UC), but is un-usual for those treated for familial adenomatous polyposis (FAP). While a number of theories as to the pathogenesis of this inflammatory condition have been proposed, no single one has been wholly satis-factory. Much research has been devoted to investi-gating a link between the pathogenic factors involved in UC, but not FAP, and those underlying pouchitis. The contribution of sulfate-producing bacteria has also been explored. The role of other intraluminal factors, such as short chain fatty acids and unconju-gated bile salts, has also been investigated. A unifying theory of a multi-step process might explain the pathogenesis of pouchitis, but further research is re-quired to proof causation. It is likely that pouchitis develops as a result of a combination of genetic, im-munological, microbial and metabolic factors. Future insight into the causes of pouchitis may eventually allow for the development of more effective treat-ments.