TITLE:
Synthesis of Novel Heteropolycyclic Nitrogen Systems Bearing Fluorine Substituted Pyrazolo[3,4-d] Pyrimidine Derived from Polyfunctional π-Acceptor Compounds and Guanidine as Fungicidal Probes
AUTHORS:
Dina A. Bakhotmah, Salwa Y. Al-Hazme
KEYWORDS:
Synthesis Polyheterocyclic, Pyrazolo[3, 4-d] Pyrimidine, Antifungal
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.9 No.1,
March
28,
2019
ABSTRACT: Novel heteropolycyclic
nitrogen systems bearing fluorine substituted pyrazolo[3,4-d] pyrimidine
moiety have been synthesis by the interaction between N’-heteroaryl guanidine 4 with
polyfunctional π-acceptors in different media and condition. The structures of
the synthesis compounds were established by spectroscopic analysis and
evaluated as antifungal probes in various concentration.