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Norris, G.J. and Benveniste, E.N. (1993) Interleukin-6 Production by Astrocytes: Induction by the Neurotransmitter Norepinephrine. Journal of Neuroimmunology, 45, 137-146.
https://doi.org/10.1016/0165-5728(93)90174-W

has been cited by the following article:

  • TITLE: Interleukins and Acute Phase Proteins of Bovine Sera during Natural Helminth Burden in Ibadan Nigeria

    AUTHORS: Olalekan Taiwo Jeremiah, Gabriel Olamilekan Banwo

    KEYWORDS: C-Reactive Protein (CRP), Interleukins, Bovine Helminthosis, Haptoglobin, Serum Amyloid A (SAA)

    JOURNAL NAME: Open Journal of Veterinary Medicine, Vol.8 No.3, March 27, 2018

    ABSTRACT: Inflammatory reactions in the gastrointestinal tract play an important role in the pathogenesis of gastroenteritis in bovine helminthosis. This study determined the serum concentrations of cytokines induced acute phase proteins (Serum Amyloid A (SAA), Haptoglobin (Hp) and C-reactive protein (CRP)) and the levels of immunoreactive interleukins (IL-1, IL-2, IL-3, IL-4, IL-5 and IL-6) in cattle naturally infected with helminths. We sampled a total of 480 slaughtered cattle of both sexes in a major abattoir in Ibadan, Nigeria. Sedimentation, floatation and modified McMaster techniques were employed to determine the degrees of helminth infections. Animals with eggs per gram (epg) less than 200 were adjudged to be apparently healthy. The serum concentrations of interleukins and acute phase proteins were determined using the Technicon AutoAnalyzer Model AA II. It was found that mean SAA (μg/l) and CRP (%) levels were significantly (P 0.05). Therefore, some acute phase proteins are involved in the pathophysiology of bovine helminthosis and are closely related to the inflammatory activation of the disease. In lieu of these findings, it is suggested that systemic markers of inflammation can identify subjects at high risk of natural bovine helminthosis and that IL-6 and SAA may be used as indicators for bovine helminthosis.