Article citationsMore>>
Fanotto, V., Ongaro, E., Rihawi, K., Avallone, A., Silvestris, N., Fornaro, L., Vasile, E., Antonuzzo, L., Leone, F., Rosati, G., Giuliani, F., Bordonaro, R., Scartozzi, M., De Maglio, G., Negri, F.V., Fasola, G. and Aprile, G. (201) HER-2 Inhibition in Gastric and Colorectal Cancers: Tangible Achievements, Novel Acquisitions and Future Perspectives. Oncotarget, 7, 69060-69074.
https://doi.org/10.18632/oncotarget.11264
has been cited by the following article:
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TITLE:
The Synergistic Effects Study of C-myc and C-erbB-2 in the Carcinogenesis of Gastric Carcinoma
AUTHORS:
Keqiang Wang, Jiangang Liu, Yanchao Duan, Shengyi Dongye, Jiafeng Wu, Yiren Wang, Zhenzhong Liu, Guoxin Han
KEYWORDS:
c-myc, c-erbB-2, Synergistic Effects
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.7 No.12,
December
28,
2017
ABSTRACT: Objective: To study the significance of c-myc and c-erbB-2 oncogene expression in gastric cancer. Methods: 81 gastric cancer specimens were detected for c-myc and c-erbB-2 oncogene amplification using non-radioactive in situ hybridization method. Results: The amplification rates for c-myc and c-erbB-2 were 67.9% and 50.6% respectively, and there were significant correlation in the amplification of these two genes (χ2 = 7.26, P Conclusions: The amplification of c-myc and c-erbB-2 may play an important role in gastric cancer development, and these two genes may have synergistic effect.
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