TITLE:
GnRH Antagonist Protocol: Is It Effective for Expected Poor Ovarian Responders with Tubal Factor Undergoing IVF?
AUTHORS:
Weijie Xing, Haiyan Lin, Qingxue Zhang
KEYWORDS:
Poor Ovarian Responders, GnRH Antagonist Protocol, GnRH Agonist Protocol
JOURNAL NAME:
Advances in Reproductive Sciences,
Vol.5 No.4,
October
24,
2017
ABSTRACT: Background: This study aimed to determine if the gonadotropin releasing hormone (GnRH) antagonist protocol is optimal for expected poor ovarian responders with tubal factor undergoing in vitro fertilization-embryo transfer (IVF-ET). Methods: A total of 341 IVF-ET cycles were retrospectively identified. The following inclusion criteria were applied: age ≥ 40 years and patients with tubal factors. The cycles were divided into two groups: a GnRH antagonist group (157 cycles) and a GnRH agonist group (184 cycles). Results: The duration of stimulation and the total doses of gonadotropin in the GnRH agonist group were significantly more than those in the GnRH antagonist group (P