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Article citations


Kameda, Y., Oira, S., Matsui, K., Kanatomo, S. and Hase, T. (1974) Antitumor Activity of Bacillus natto V. Isolation and Characterization of Surfactin in the Culture Medium of Bacillus natto KMD 2311. Chemical and Pharmaceutical Bulletin, 22, 938-944.

has been cited by the following article:

  • TITLE: Physicochemical Properties and Fibrinolytic Activity of Ginseng Powder Fermented with Bacillus subtilis Isolated from Cheonggukjang

    AUTHORS: Jiyun Jeong, Youngkyoung Rhee, Sungsoo Kim

    KEYWORDS: Bacillus subtilis, Fermentation, Fibrinolytic activity, Ginseng, Ginsenoside

    JOURNAL NAME: American Journal of Plant Sciences, Vol.8 No.8, July 17, 2017

    ABSTRACT: In order to obtain all the properties of fermented ginseng, we fermented ginseng using Bacillus subtilis (B. subtilis) isolated from Cheonggukjang. A sterilized ginseng medium was made with 4-year-old ginseng powder and distilled water (300% ginseng powder [w/w]), and the ginseng was fermented by B. subtilis (1% ginseng medium) followed by incubation at 37°C for 3, 5, 7, and 10 days. The growth of B. subtilis in the ginseng medium significantly increased up to 9 log CFU/g, but no significant difference was observed after 3 days. As the fermentation progressed, the ginsenoside Rd and Rg+Rh1 contents increased by 255.3% - 322.5% and 165.6% - 228.6%, respectively, whereas the Rc, Re, and Rg1 contents decreased by 30.7% - 39.6%, 10.5% - 12.8%, and 16.2% - 16.6%, respectively. After 3 days of fermentation, a 6.25% - 7.12% viscous substance was produced; thereafter, the viscous substance was gradually reduced until it disappeared. The viscosity of the medium significantly decreased with a longer fermentation time. Fibrinolytic activity increased during 3 - 10 days of fermentation, indicating a relative activity of 85.0% - 100.0%.