SCIRP Mobile Website
Paper Submission

Why Us? >>

  • - Open Access
  • - Peer-reviewed
  • - Rapid publication
  • - Lifetime hosting
  • - Free indexing service
  • - Free promotion service
  • - More citations
  • - Search engine friendly

Free SCIRP Newsletters>>

Add your e-mail address to receive free newsletters from SCIRP.


Contact Us >>

WhatsApp  +86 18163351462(WhatsApp)
Paper Publishing WeChat
Book Publishing WeChat

Article citations


Ficociello, L.H., Rosolowsky, E.T., Niewczas, M.A., Maselli, N.J., Weinberg, J.M, Aschengrau, A., et al. (2010) High-Normal Serum Uric Acid Increases Risk of Early Progressive Renal Function Loss in Type 1 Diabetes: Results of a 6-Year Follow-Up. Diabetes Care, 33, 1337-1343.

has been cited by the following article:

  • TITLE: Hyperuricemia as a Predictor of Progression of Chronic Kidney Disease: A Matched Cohort Analysis

    AUTHORS: Michiaki Kamiyama, Hiroshi Kataoka, Takahito Moriyama, Toshio Mochizuki, Kosaku Nitta

    KEYWORDS: CKD, Hyperuricemia, Propensity Score Matching, Visceral Fat Area, Maximum Carotid Intima-Media Thickness

    JOURNAL NAME: International Journal of Clinical Medicine, Vol.8 No.3, March 31, 2017

    ABSTRACT: Background: The clinical significance of uric acid (UA) in patients with chronic kidney disease (CKD) has never been elucidated in detail. Objectives: The aim of this study was to elucidate the predictive value of hyperuricemia (HU) in relation to kidney disease progression in CKD patients. Methods: We reviewed data obtained from 201 CKD patients. Renal outcome was assessed by performing the Kaplan-Meier and Cox proportional hazard regression models. The renal outcomes of CKD patients with and without HU were compared by using a propensity score-matched cohort. Results: The results of a multivariate Cox regression analysis showed that HU (UA ≥ 7.1 mg/dL) (P = 0.001), diabetes mellitus (P = 0.003), and a high urine albumin-to-creatinine ratio (P = 0.0005) were significantly associated with a ≥50% eGFR decline or ESRD. The serum UA values were positively correlated with mean blood pressure (P = 0.007), visceral fat area (P = 0.0003), and maximum carotid intima-media thickness (P = 0.0003). The Kaplan-Meier analysis in the propensity score-matched cohort indicated that the renal survival rate of the group of CKD patients with HU was significantly lower than that of the group without HU (log rank, P Conclusion: The results of this study suggest that the serum UA value is a predictor of CKD progression.