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Article citations


Mullins, P.G., McGonigle, D.J., O’Gorman, R.L., Puts, N.A., Vidyasagar, R., Evans, C.J. and Edden, R.A. (2014) Current Practice in the Use of MEGA-PRESS Spectroscopy for the Detection of GABA. NeuroImage, 86, 43-52.

has been cited by the following article:

  • TITLE: Voxel Placement Precision for GABA-Edited Magnetic Resonance Spectroscopy

    AUTHORS: Xue Bai, Ashley D. Harris, Tao Gong, Nicolaas A. J. Puts, Guangbin Wang, Michael Schär, Peter B. Barker, Richard A. E. Edden

    KEYWORDS: MRS, Voxel Placement, Precision, Voxel Prescription, Registration

    JOURNAL NAME: Open Journal of Radiology, Vol.7 No.1, March 24, 2017

    ABSTRACT: The purpose of the present study was to assess the reproducibility of voxel placement for GABA-edited MRS. GABA-edited MRS data were acquired in 13 healthy volunteers from (3 cm)3 voxel; and within the same session a second acquisition was independently prescribed. A three-dimensional voxel mask image was reconstructed in T1-image-space using the SVMask tool (in house software). Reproducibility of voxel placement was assessed using the Dice overlap coefficient, both within-subject and between-subject following co-registration of T1 images and transformation of voxel mask images to standard space. Within-subject overlap coefficients were 86% ± 5%. Between-subject overlap coefficients were 75% ± 10%. For the two voxel locations considered (occipital and sensorimotor), voxel overlap was very similar. Between-subject values are higher due to between-session effects, anatomical variability and volume mismatch in standard space. While surprisingly low in terms of volume overlap, the overlap coefficients correspond to acceptable linear displacements.