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Article citations


Sing, A., Tuschak, C. and Hormansdorfer, S. (2008) Methicillin Resistant Staphylococcus aureus in a Family and Its Pet Cat. The New England Journal of Medicine, 358, 1200-1201.

has been cited by the following article:

  • TITLE: Co-Habitation of Staphylococcus lugdunensis with Staphylococcus aureus Resistant to Methicillin and Vancomycin in the Nasal Snares of Laboratory Rats

    AUTHORS: Lorina Ineta Badger-Emeka

    KEYWORDS: Nasal, Staphylococcus lugdunensis, Staphylococcus aureus, Methicillin, Vancomycin Resistance, Rats

    JOURNAL NAME: Advances in Microbiology, Vol.7 No.1, January 13, 2017

    ABSTRACT: The public health problem created by multidrug resistant bacteria in the 21st century continues to receive attention by researchers all over the world. As the production of new antibiotics is not commeasurable with the rate of evolvement of MDR bacteria, the news of a proposed new antibiotic “Lugdunin” is much awaited and a welcomed development. Lugdunin is produced by Staphylococcus lugdunensis and has the ability to kill S. aureus. Both bacteria are nasal colonizers. The present investigation looks into the antibiotic susceptibility pattern of co-habitation of S. lugdunensis with methicillin and vancomycin resistant Staphylococcus aureus in laboratory bred Wister rats. Nasal swabs of anaesthetized rats were collected using a sterile cotton swab moistened in 0.9% saline solution. All swabs were inoculated into nutrient broth, cultured at 37°C for 24 hrs. Overnight bacterial growth plated on blood agar and incubated at 37°C for 24 hrs. Organism identification and antibiotic susceptibility test were by using BioMerieux VITEK 2 compact automated system (BioMerieux, Marcy I’Etoile France), according to the manufacturers guidelines. Results obtained showed co-habitation of S. aureus with co-agulase negative bacteria, inclusive of S. lugdunensis. All the isolates were resistant to methicillin with a 33.3% resistance to vancomycin. The difference between the number of antibiotic resistant or sensitive varied statistically among the Staphylococcal isolates. For S. aureus 1, the difference was significant with p-value 0.034 but not significant for isolates 2, 3 and 4 with p-values of 0.158, 0.477 and 0.158 respectively. A statistically significant difference was seen with S. lugdunensis. The result from the study therefore, showed that the colonization of the nasal snares of the laboratory bred rats with S. aureus and other co-agulase negative Staphylococci was not affected by the presence of S. lugdunensis.