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Reif, A., Schmitt, A., Fritzen, S. and Lesch, K.P. (2007) Neurogenesis and Schizophrenia: Dividing Neurons in a Divided Mind? European Archives of Psychiatry and Clinical Neurosciences, 257, 290-299. http://dx.doi.org/10.1007/s00406-007-0733-3

has been cited by the following article:

  • TITLE: Understanding the Etiology and Treatment Approaches of Schizophrenia: Theoretical Perspectives and Their Critique

    AUTHORS: Minjeong Kim

    KEYWORDS: Schizophrenia, Theory, Neurobiology

    JOURNAL NAME: Open Journal of Psychiatry, Vol.6 No.4, October 24, 2016

    ABSTRACT: This paper reviewed genetic, neurodevelopmental, and neurobiological perspectives to understand the etiology and relevant treatment approaches of schizophrenia. Although genetic and neurodevelopmental theories provide a substantial contribution to the etiology of schizophrenia, neurobiological one has its dominant stance in which it can explain causative mechanisms of schizophrenia, identify targets for treatment, and predict outcomes well. According to the neurobiology, onset and course of schizophrenia are well supported by the alterations in neurotransmitters such as dopamine or serotonin. Based on this mechanism, antipsychotics have been widely used as one of the treatment approaches for schizophrenia. By following up the degree of patients’ responses to antipsychotics, treatment outcomes could be evaluated or predicted. Although neurobiology seldom provides information about identification or prevention of risk factors about schizophrenia compared to genetic and neurodevelopmental approaches, it has well-established scientific foundations, ability to guide treatment, applicability across age and culture, and usefulness as a research framework.