Solis Herrera, A., Arias-Sparza, M.C., Solis Arias, P.E., ávila-Rodrigues, M., Barreto, G.E., Li, Y., Bachurin, S.O. and Gjumrakch, A. (2016) The Unsuspected Intrinsic Property of Melanin to Dissociate Water Can Be Used for the Treatment of Neurological Diseases. CNS & Neurological Disorders—Drug Targets, 15, 135-140.
http://dx.doi.org/10.2174/1871527315666160202122943

has been cited by the following article:

• TITLE: Macroscopic Self-Organized Electrochemical Patterns in Excitable Tissue and Irreversible Thermodynamics

  AUTHORS: Vera Maura Fernandes de Lima, Wolfgang Hanke

  KEYWORDS: Brain Self-Organization, Non-Linear Thermodynamics, Membrane Phase Transitions, Memory and Learning

  JOURNAL NAME: Open Journal of Biophysics, Vol.6 No.4, September 20, 2016

  ABSTRACT: In this paper we make the assertion that the key to understand the emergent properties of excitable tissue (brain and heart) lies in the application of irreversible thermodynamics. We support this assertion by pointing out where symmetry break, phase transitions both in structure of membranes as well as in the dynamic of interactions between membranes occur in excitable tissue and how they create emergent low dimensional electrochemical patterns. These patterns are expressed as physiological or physiopathological concomitants of the organ or organism behavior. We propose that a set of beliefs about the nature of biological membranes and their interactions are hampering progress in the physiology of excitable tissue. We will argue that while there is no direct evidence to justify the belief that quantum mechanics has anything to do with macroscopic patterns expressed in excitable tissue, there is plenty of evidence in favor of irreversible thermodynamics. Some key predictions have been fulfilled long time ago and they have been ignored by the mainstream literature. Dissipative structures and phase transitions appear to be a better conceptual context to discuss biological self-organization. The central role of time as a global coupling agent is emphasized in the interpretation of the presented results.