SCIRP Mobile Website
Paper Submission

Why Us? >>

  • - Open Access
  • - Peer-reviewed
  • - Rapid publication
  • - Lifetime hosting
  • - Free indexing service
  • - Free promotion service
  • - More citations
  • - Search engine friendly

Free SCIRP Newsletters>>

Add your e-mail address to receive free newsletters from SCIRP.

 

Contact Us >>

Article citations

More>>

McLennan, J. and Darby, G. (1980) Herpes Simplex Virus Latency: The Cellular Location of Virus in Dorsal Root Ganglia and the Fate of the Infected Cell Following Virus Activation. Journal of General Virology, 51, 233-243.
http://dx.doi.org/10.1099/0022-1317-51-2-233

has been cited by the following article:

  • TITLE: Herpes Simplex Virus 1, Cytomegalovirus and Epstein Barr Virus Detection in Patients with Chronic and Aggressive Periodontitis

    AUTHORS: Harold H. Hernández, Andreína S. Fernandes, Laura A. Escalona, María Correnti

    KEYWORDS: Periodontitis, Gingival Crevicular Fluid, Cytomegalovirus, Herpes Simplex Virus, Epstein Barr Virus

    JOURNAL NAME: Open Access Library Journal, Vol.3 No.3, March 25, 2016

    ABSTRACT: Recent investigations suggest that the viruses of the family Herpesviridae are associated with periodontal disease, demonstrating a possible association with the presence of Human Cytomegalovirus (HCMV), Herpes Simplex Virus 1 (HSV-1) and Epstein Barr Virus (EBV) in periodontal tissues. Aim: To analyze the association between the presence of HSV-1, HCMV and EBV in patients with chronic or aggressive periodontitis. Methods: Crevicular fluid samples were collected from 11 patients with aggressive periodontitis (AgP), 11 with chronic periodontitis (CP) and 11 healthy control subjects (CG). The following clinical parameters were measured: plaque index (PI), bleeding on probing (BOP), probing depths (PD) and clinical attachment loss (CAL). Viral detection was performed by PCR for HSV-1, HCMV and EBV. Results: HCMV was detected in 27.3% of AgP patients but not detected in CP and healthy subjects; HSV-1 in 27.3% of AgP and CP group and in 9.1% of CG. EBV-1 was detected in 18.2% of CP patients and 9.1% of the CG. HCMV and HSV-1 coinfection was detected in 18.8% of AgP patients and 9.09% of viral coinfection between HSV-1 and VEB, within the CP group. The AgP group exhibited the higher values for all clinical parameters evaluated, respect to the CP and control group. Conclusion: The presence of HCMV may be related to periodontal disease, specifically in cases of AgP, and it may play a synergistic role with other infectious agents from the oral cavity associated with the development of periodontitis.