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Article citations


Sun, J.L., Gao, G.L., Zhao, Y., Gao, Y.L., Xiong, L.J., et al. (2013) Elderly Patients and Coronary Heart Disease on Response to Treadmill Exercise Test. Cell Biochemistry and Biophysics, 67, 965-968.

has been cited by the following article:

  • TITLE: Analysis of Serum Biochemical Indexes for the Diagnosis of Coronary Heart Disease in Suspected Patients

    AUTHORS: Hongcheng Mai, Zhifeng Huang, Tao Zhang

    KEYWORDS: Treadmill Exercise Test, Coronary Angiography, Receiver Operating Characteristic, Glycated Hemoglobin, Coronary Heart Disease, Low-Density Protein

    JOURNAL NAME: Open Access Library Journal, Vol.3 No.3, March 2, 2016

    ABSTRACT: Background: The serum biochemical indexes are classic detection in clinical practice. Methods: In this study, for avoiding the risks of serious complications, high-cost in diagnosis of suspected coronary heart disease (CHD), the common biochemical indexes were detected from 68 eligible patients with suspected CHD. Treadmill exercises test (TET)-electrocardiogram (ECG) was measured during TET, and invasive examination of coronary angiography (CAG, golden standard for CHD diagnosis) was also performed. Results: For CAG, 48 patients were positive and 20 were negative; while for TET 38 were positive, 14 were inconclusive, and 16 were negative, respectively. Among these biochemical indexes, the HbA1c (%) level in CAG positive patients was much higher than that in CAG negative patients (P = 0.019). Furthermore, according to receiver operating characteristic (ROC) curve, HbA1c showed effective diagnosis for CHD and its best cutoff value was 5.85% and 29 of the patients were HbA1c positive and 30 were negative. Conclusions: It was found that HbA1c combined with TET obviously enhanced the sensitivity of examinations. All the patients who were negative in both HbA1c and TET tests turned out to be 90% CAG negative, which meant that the combination might stand invasive examination of CAG for CHD diagnosis. Further studies in multi-center investigation will be expected to validate the findings.